Sperm Vacuoles and Reproductive Outcome

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Sperm Vacuoles and Reproductive Outcome

It is estimated that the male factor contributes to half of the infertility in couples attending for assisted reproductive techniques (ART). Therefore the semen analysis remains the starting point to evaluate main causes of infertility and in case of oligospermic semen the assessment of sperm morphology may help to choose the best spermatozoon to use for the intracytoplasmic sperm injection (IC...

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Does the presence of nuclear vacuoles in human sperm selected for ICSI affect pregnancy outcome?

BACKGROUND To verify whether or not microinjection of sperm with a normal nuclear shape but large vacuoles affects IVF-ICSI pregnancy outcome. METHODS A comparative study testing IVF outcome parameters of IVF-ICSI, based on morphological selection of spermatozoa with normal nuclei against those based on microinjection of sperm with a normal nuclear shape but large vacuoles. An experimental gr...

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Re: sperm vacuoles are linked to capacitation and acrosomal status.

STUDY QUESTION Is the presence of nuclear vacuoles really a negative parameter? SUMMARY ANSWER As sperm vacuoles are associated with acrosomal and capacitation status, they appear to be a reflection of normal sperm physiology. WHAT IS KNOWN ALREADY The selection of sperm under a high magnification has been proposed as a strategy to increase the success rates of ICSI, through a better select...

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Sperm morphology and reproductive success

fertilization potential, decisions on how to improve sperm morphology remain difficult to address. Smoking, alcohol consumption, caffeine intake and drug use can affect fertility; however, a conclusive connection between these factors and sperm morphology has not been demonstrated. Furthermore, use of dietary supplements and vitamins has not been shown to directly affect sperm morphology. While...

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Observation of sperm-head vacuoles and sperm morphology under light microscope

OBJECTIVE The presence of sperm-head vacuoles has been suspected to be deleterious to the outcomes of assisted reproductive technology (ART). It is difficult to accurately distinguish morphologically abnormal sperm with vacuoles under a light microscope. This study was performed to analyze the result of the observation of sperm-head vacuoles using Papanicolaou staining under a light microscope ...

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ژورنال

عنوان ژورنال: Journal of Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biology

سال: 2015

ISSN: 2375-4508

DOI: 10.4172/2375-4508.1000e118